New phenolic compounds from Vitex negundo var. heterophylla and their antioxidant and NO inhibitory activities

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Antioxidant and Antiinflammatory Activity of Vitex negundo

Reactive oxygen species are implicated in various inflammatory disorders. Vitex negundo is mentioned in Ayurveda as useful in treating arthritic disorders. The present work was undertaken to evaluate the antioxidant potential and anti-inflammatory activity of the plant. The total methanol extract of the plant was standardized in terms of total polyphenols. The standardized extract in a dose of ...

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Antiseptic activity and phenolic constituents of the aerial parts of Vitex negundo var. cannabifolia.

Four phenolics, salviaplebeiaside (1), γ-tocopherol (2), chrysosplenol-D (4), and isovitexin (5), along with α-tocoquinone (3) and β-sitosterol (6) were isolated from the aerial parts of Vitex negundo var. cannabifolia. The isolation was performed using bio-assay tracking experiments. The structures of compounds 1-5 were established by spectroscopic means. The antibacterial activities of the co...

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Anti-inflammatory Activity of Extracts and Compounds from Vitex Negundo

RASADAH, M. A., FAREDIAH, A., WONG, C. L. & ONG, B. K. 2005. Antiinflammatory activity of extracts and compounds from Vitex negundo. The antiinflammatory activity of the leaf extract of Vitex negundo was investigated on topical administration using the TPA (tetradecanoylphorbol acetate)-induced mouse ear inflammation model. The crude methanolic extract of V. negundo showed moderate inhibition (...

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Total phenolic compounds and scavenging activity in Clitoria ternatea and Vitex negundo linn

This study was done to assess the total phenolic compounds (TPC) and 1, 1-diphenyl-2picrylhydrazyl (DPPH) scavenging activity in the flowers and leaves of Clitoria ternatea and Vitex negundo Linn. by using methanol and water extraction. TPC were evaluated using Folin-Ciocalteau method. Methanol was more efficient in extracting phenolic compounds compared with water in measuring TPC. Vitex negun...

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A new labdane diterpene from Vitex negundo.

CONTEXT Vitex negundo Linn. (Verbenaceae) seeds are pepper substitute and occasionally used as a condiment for edible purposes. The seeds also find use for analgesia, sedation, rheumatism and joint inflammation in folk medicine. OBJECTIVE To isolate and characterize bioactive constituents from V. negundo seeds. MATERIALS AND METHODS The ethanol extract of V. negundo seeds was subjected to r...

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ژورنال

عنوان ژورنال: Journal of Functional Foods

سال: 2015

ISSN: 1756-4646

DOI: 10.1016/j.jff.2015.09.016